The Who, What, When, and Where of Inpatient Direct Oral Penicillin Challenge - Implications for Health Services Implementation

JA Trubiano; S Vogrin; E Mitri; R Hall; A Copaescu; J Waldron; J De Luca; M Rose; G Mackay; B Lambros; AP Douglas; NE Holmes; KYL Chua

Journal article

The Who, What, When, and Where of Inpatient Direct Oral Penicillin Challenge - Implications for Health Services Implementation

JA Trubiano, S Vogrin, E Mitri, R Hall, A Copaescu, J Waldron, J De Luca, M Rose, G Mackay, B Lambros, AP Douglas, NE Holmes, KYL Chua

Clinical Infectious Diseases | OXFORD UNIV PRESS INC | Published : 2023

DOI: 10.1093/cid/ciad156

Abstract

Inpatient direct oral challenge programs are increasingly deployed as part of antimicrobial stewardship initiatives to reduce the burden and impacts of penicillin allergy labels on antibiotic prescribing. Using data from a prospective, multicenter cohort inpatient penicillin allergy program, we identify the key targets for delabeling to aid health service implementation.

University of Melbourne Researchers

Jason Trubiano Author

Sara Vogrin Author

Morgan Rose Author

Natasha Holmes Author

Related Projects (1)

DEVELOPING AND EVALUATING A MULTIMODAL ANTIBIOTIC ALLERGY STRATEGY TO IMPROVE ANTIMICROBIAL STEWARDSHIP IN HIGH-RISK ANTIBIOTIC USAGE POPULATIONS

Antibiotic allergies lead to the use of inferior antibiotics and generation of “superbugs”. Antibiotic allergy testing removes up to 90% of ..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

This work was supported by Better Care Victoria Innovation Fund, Better Care Victoria, Department of Health Victoria, Australia. J. A. T. is supported by a National Health and Medical Research Council Emerging Leadership Fellowship (1139902).